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Fyn Activation of mTORC1 Stimulates the IRE1α-JNK Pathway, Leading to Cell Death
We previously reported that the skeletal muscle-specific overexpression of Fyn in mice resulted in a severe muscle wasting phenotype despite the activation of mTORC1 signaling. To investigate the bases for the loss of muscle fiber mass, we examined the relationship between Fyn activation of mTORC1,...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4598989/ https://ncbi.nlm.nih.gov/pubmed/26306048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.687020 |
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