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Fyn Activation of mTORC1 Stimulates the IRE1α-JNK Pathway, Leading to Cell Death
We previously reported that the skeletal muscle-specific overexpression of Fyn in mice resulted in a severe muscle wasting phenotype despite the activation of mTORC1 signaling. To investigate the bases for the loss of muscle fiber mass, we examined the relationship between Fyn activation of mTORC1,...
Shranjeno v:
| izdano v: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4598989/ https://ncbi.nlm.nih.gov/pubmed/26306048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.687020 |
| Oznake: |
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