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Mechanisms Involved in the Coordinate Regulation of mTORC1 by Insulin and Amino Acids

In this study, we explored the coordinate regulation of mTORC1 by insulin and amino acids. Rat livers were perfused with medium containing various concentrations of insulin and/or amino acids. At fasting (1×) or 2× (2×AA) concentrations of amino acids, insulin maximally stimulated Akt phosphorylatio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dennis, Michael D., Baum, Jamie I., Kimball, Scot R., Jefferson, Leonard S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048714/
https://ncbi.nlm.nih.gov/pubmed/21239491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.209171
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