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ERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signaling

The mammalian target of rapamycin (mTOR) is a protein kinase that, when present in a complex referred to as mTOR complex 1 (mTORC1), acts as an important regulator of growth and metabolism. The activity of the complex is regulated through multiple upstream signaling pathways, including those involvi...

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Detalhes bibliográficos
Main Authors: Winter, Jeremiah N., Jefferson, Leonard S., Kimball, Scot R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093949/
https://ncbi.nlm.nih.gov/pubmed/21289294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00504.2010
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