mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway

Mammalian target of rapamycin (mTOR) has a key role in the regulation of an array of cellular function. We found that rapamycin, an inhibitor of mTOR complex 1 (mTORC1), attenuated endoplasmic reticulum (ER) stress-induced apoptosis. Among three major branches of the unfolded protein response, rapam...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Kato, H, Nakajima, S, Saito, Y, Takahashi, S, Katoh, R, Kitamura, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263505/
https://ncbi.nlm.nih.gov/pubmed/21779001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.98
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars