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Microdialysis Measurement of Intratumoral Temozolomide Concentration after Cediranib, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, in a U87 Glioma Model
BACKGROUND: Combining anti-angiogenesis agents with cytotoxic agents for the treatment of malignant gliomas, may affect the cytotoxic drug distribution by normalizing the blood brain-barrier (BBB). This study examines the intratumoral concentration of temozolomide (TMZ) in the presence and absence o...
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| Pubblicato in: | Cancer Chemother Pharmacol |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4596243/ https://ncbi.nlm.nih.gov/pubmed/23649683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-013-2172-3 |
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