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The impact of bevacizumab on temozolomide concentrations in intracranial U87 gliomas

PURPOSE: An important question in the sequencing of anti-cancer therapies in patients with glioblastoma (GBM) is whether concurrent anti-angiogenesis therapies improve or impair brain concentrations of concomitantly administered cytotoxic therapies. The purpose of this study is to assess the intratu...

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Detalhes bibliográficos
Main Authors: Grossman, Rachel, Rudek, Michelle A., Brastianos, Harry, Zadnik, Patti, Brem, Henry, Tyler, Betty, Blakeley, Jaishri O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005329/
https://ncbi.nlm.nih.gov/pubmed/22644796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-012-1867-1
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