Combination of anti-VEGF therapy and temozolomide in two experimental human glioma models

Anti-angiogenic agents, such as bevacizumab (BEV), can induce normalization of the blood brain barrier, which may influence the penetration and activity of a co-administered cytotoxic drug. However, it is unknown whether this effect is associated with a benefit in overall survival. This study employ...

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Bibliografiska uppgifter
Huvudupphovsmän: Grossman, Rachel, Brastianos, Harry, Blakeley, Jaishri O., Mangraviti, Antonella, Lal, Bachchu, Zadnik, Patti, Hwang, Lee, Wicks, Robert T., Goodwin, Rory C., Brem, Henry, Tyler, Betty
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037922/
https://ncbi.nlm.nih.gov/pubmed/24185441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-013-1268-2
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