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Microdialysis for assessing intratumoral drug disposition in brain cancers: a tool for rational drug development

IMPORTANCE OF THE FIELD: Many promising targeted agents and combination therapies are being investigated for brain cancer. However, the results from recent clinical trials have been disappointing. A better understanding of the disposition of drug in the brain early in drug development would facilita...

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Detalhes bibliográficos
Main Authors: Blakeley, Jaishri, Portnow, Jana
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994531/
https://ncbi.nlm.nih.gov/pubmed/20969450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2010.523420
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