Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds

Tuberculosis (TB) remains a worldwide problem and the need for new drugs is increasingly more urgent with the emergence of multidrug- and extensively-drug resistant TB. Inosine 5’-monophosphate dehydrogenase 2 (IMPDH2) from Mycobacterium tuberculosis (Mtb) is an attractive drug target. The enzyme ca...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Makowska-Grzyska, Magdalena, Kim, Youngchang, Gorla, Suresh Kumar, Wei, Yang, Mandapati, Kavitha, Zhang, Minjia, Maltseva, Natalia, Modi, Gyan, Boshoff, Helena I., Gu, Minyi, Aldrich, Courtney, Cuny, Gregory D., Hedstrom, Lizbeth, Joachimiak, Andrzej
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594927/
https://ncbi.nlm.nih.gov/pubmed/26440283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138976
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items