Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH

Cryptosporidium parasites are important waterborne pathogens of both humans and animals. The C. parvum and C. hominis genomes indicate that the only route to guanine nucleotides is via inosine 5'-monophosphate dehydrogenase (IMPDH). Thus the inhibition of the parasite IMPDH presents a potential...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Kirubakaran, Sivapriya, Gorla, Suresh Kumar, Sharling, Lisa, Zhang, Minjia, Liu, Xiaoping, Ray, Soumya S., MacPherson, Iain S., Striepen, Boris, Hedstrom, Lizbeth, Cuny, Gregory D.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289519/
https://ncbi.nlm.nih.gov/pubmed/22310229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.01.029
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares