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Structure of a bacterial RNA polymerase holoenzyme open promoter complex

Initiation of transcription is a primary means for controlling gene expression. In bacteria, the RNA polymerase (RNAP) holoenzyme binds and unwinds promoter DNA, forming the transcription bubble of the open promoter complex (RPo). We have determined crystal structures, refined to 4.14 Å-resolution,...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Bae, Brian, Feklistov, Andrey, Lass-Napiorkowska, Agnieszka, Landick, Robert, Darst, Seth A
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593229/
https://ncbi.nlm.nih.gov/pubmed/26349032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08504
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