RNA polymerase motions during promoter melting

All cellular RNA polymerases (RNAPs), from those of bacteria to those of man, possess a clamp that can open and close, and it has been assumed that the open RNAP separates promoter DNA strands and then closes to establish a tight grip on the DNA template. Here, we resolve successive motions of the i...

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Publicado no:Science
Main Authors: Feklistov, Andrey, Bae, Brian, Hauver, Jesse, Lass-Napiorkowska, Agnieszka, Kalesse, Markus, Glaus, Florian, Altmann, Karl-Heinz, Heyduk, Tomasz, Landick, Robert, Darst, Seth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696265/
https://ncbi.nlm.nih.gov/pubmed/28546214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aam7858
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