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Structural basis for promoter –10 element recognition by the bacterial RNA polymerase σ subunit
The key step in bacterial promoter opening is recognition of the -10 promoter element (T(-12)A(-11)T(-10)A(-9)A(-8)T(-7) consensus sequence) by the RNA polymerase σ subunit. We determined crystal structures of σ domain 2 bound to single-stranded DNA bearing -10 element sequences. Extensive interacti...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245737/ https://ncbi.nlm.nih.gov/pubmed/22136875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.10.041 |
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