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Promoter recognition by bacterial alternative σ factors: the price of high selectivity?

A key step in bacterial transcription initiation is melting of the double-stranded promoter DNA by the RNA polymerase holoenzyme. Primary σ factors mediate the melting of thousands of promoters through a conserved set of aromatic amino acids. Alternative σs, which direct transcription of restricted...

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Autori principali: Feklistov, Andrey, Darst, Seth A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764498/
https://ncbi.nlm.nih.gov/pubmed/19833764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1862609
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