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Crystallographic analysis of an RNA polymerase σ-subunit fragment complexed with −10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein–ssDNA complexes
Structural studies of −10 promoter element recognition by domain 2 of the RNA polymerase σ subunit [Feklistov & Darst (2011 ▶), Cell, 147, 1257–1269] reveal an unusual crystal-packing arrangement dominated by G-quartets. The 3′-terminal GGG motif of the oligonucleotide used in crystallization pa...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
International Union of Crystallography
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758139/ https://ncbi.nlm.nih.gov/pubmed/23989139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113020368 |
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