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Structure of a bacterial RNA polymerase holoenzyme open promoter complex

Initiation of transcription is a primary means for controlling gene expression. In bacteria, the RNA polymerase (RNAP) holoenzyme binds and unwinds promoter DNA, forming the transcription bubble of the open promoter complex (RPo). We have determined crystal structures, refined to 4.14 Å-resolution,...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Bae, Brian, Feklistov, Andrey, Lass-Napiorkowska, Agnieszka, Landick, Robert, Darst, Seth A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593229/
https://ncbi.nlm.nih.gov/pubmed/26349032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08504
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