High-Dose Sirolimus And Immune Selective Pentostatin Plus Cyclophosphamide Conditioning Yields Stable Mixed Chimerism and Insufficient Graft-Versus-Tumor Responses

PURPOSE: We hypothesized that lymphoid-selective host conditioning and subsequent adoptive transfer of sirolimus-resistant allogeneic T cells (T-Rapa), when combined with high-dose sirolimus drug therapy in vivo, would safely achieve anti-tumor effects while avoiding GVHD. EXPERIMENTAL DESIGN: Patie...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Clin Cancer Res
Autors principals: Mossoba, Miriam E., Halverson, David C., Kurlander, Roger, Schuver, Bazetta Blacklock, Carpenter, Ashley, Hansen, Brenna, Steinberg, Seth M., Ali, Syed Abbas, Tageja, Nishant, Hakim, Frances T., Gea-Banacloche, Juan, Sportes, Claude, Hardy, Nancy M., Hickstein, Dennis D., Pavletic, Steven Z., Khuu, Hanh, Sabatini, Marianna, Stroncek, David, Levine, Bruce L., June, Carl H., Mariotti, Jacopo, Rixe, Olivier, Fojo, Antonio Tito, Bishop, Michael R., Gress, Ronald. E., Fowler, Daniel H.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592398/
https://ncbi.nlm.nih.gov/pubmed/26071480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0340
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars