DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID

Changes in DNA methylation are required for the formation of germinal centers (GC), but the mechanisms of such changes are poorly understood. Activation-induced cytidine deaminase (AID) has been recently implicated recently in DNA demethylation through its deaminase activity coupled with DNA repair....

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Publicat a:Cell Rep
Autors principals: Dominguez, Pilar M., Teater, Matt, Chambwe, Nyasha, Kormaksson, Matthias, Redmond, David, Ishii, Jennifer, Vuong, Bao, Chaudhuri, Jayanta, Melnick, Ari, Vasanthakumar, Aparna, Godley, Lucy A., Papavasiliou, F Nina, Elemento, Olivier, Shaknovich, Rita
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591215/
https://ncbi.nlm.nih.gov/pubmed/26365193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.036
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