DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation

The phenotype of germinal center (GC) B cells includes the unique ability to tolerate rapid proliferation and the mutagenic actions of activation induced cytosine deaminase (AICDA). Given the importance of epigenetic patterning in determining cellular phenotypes, we examined DNA methylation and the...

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Detalhes bibliográficos
Main Authors: Shaknovich, Rita, Cerchietti, Leandro, Tsikitas, Lucas, Kormaksson, Matthias, De, Subhajyoti, Figueroa, Maria E., Ballon, Gianna, Yang, Shao Ning, Weinhold, Nils, Reimers, Mark, Clozel, Thomas, Luttrop, Karin, Ekstrom, Tomas J., Frank, Jared, Vasanthakumar, Aparna, Godley, Lucy A., Michor, Franziska, Elemento, Olivier, Melnick, Ari
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186332/
https://ncbi.nlm.nih.gov/pubmed/21828137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-357996
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