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FRET-based cholesterolysis assay identifies a novel hedgehog inhibitor
Hedgehog (Hh) proteins function in cell/cell signaling processes linked to human embryo development and the progression of several types of cancer. Here we describe an optical assay of hedgehog cholesterolysis, a unique autoprocessing event critical for Hh function. The assay uses a recombinant FRET...
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| Publicado no: | Anal Biochem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4591182/ https://ncbi.nlm.nih.gov/pubmed/26095399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2015.06.021 |
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