A carregar...
Hedgehog Proteins Consume Steroidal CYP17A1 Antagonists: Potential Therapeutic Significance in Advanced Prostate Cancer
Abiraterone, a potent inhibitor of the human enzyme CYP17A1 (cytochrome P450c17), provides a last line of defense against ectopic androgenesis in advanced prostate cancer. Herein we report an unprecedented off-target interaction between abiraterone and oncogenic hedgehog proteins. Our experiments in...
Na minha lista:
| Publicado no: | ChemMedChem |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5588864/ https://ncbi.nlm.nih.gov/pubmed/27435344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600238 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|