B cell autophagy mediates TLR7-dependent autoimmunity and inflammation

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease, defined by loss of B cell self-tolerance that results in production of antinuclear antibodies (ANA) and chronic inflammation. While the initiating events in lupus development are not well defined, overexpression of the RNA-rec...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Weindel, Chi G, Richey, Lauren J, Bolland, Silvia, Mehta, Abhiruchi J, Kearney, John F, Huber, Brigitte T
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590645/
https://ncbi.nlm.nih.gov/pubmed/26120731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1052206
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