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Autophagy in dendritic cells and B cells is critical for the inflammatory state of TLR7-mediated autoimmunity

Individuals suffering from autoimmune disorders possess a hyperactive cellular phenotype where tolerance to self-antigens is lost. Autophagy has been implicated in both the induction and prevention of autoimmunity, and modulators of this cellular recycling process hold high potential for the treatme...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Weindel, Chi G., Richey, Lauren J., Mehta, Abhiruchi J., Shah, Mansi, Huber, Brigitte T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263064/
https://ncbi.nlm.nih.gov/pubmed/28031336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601307
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