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The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4

Peripheral neuropathy is dose limiting in paclitaxel cancer chemotherapy and can result in both acute pain during treatment and chronic persistent pain in cancer survivors. The hypothesis tested was that paclitaxel produces these adverse effects at least in part by sensitizing transient receptor pot...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Neurosci
Main Authors: Li, Yan, Adamek, Pavel, Zhang, Haijun, Tatsui, Claudio Esteves, Rhines, Laurence D., Mrozkova, Petra, Li, Qin, Kosturakis, Alyssa K., Cassidy, Ryan M., Harrison, Daniel S., Cata, Juan P., Sapire, Kenneth, Zhang, Hongmei, Kennamer-Chapman, Ross M., Jawad, Abdul Basit, Ghetti, Andre, Yan, Jiusheng, Palecek, Jiri, Dougherty, Patrick M.
פורמט: Artigo
שפה:Inglês
יצא לאור: Society for Neuroscience 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588613/
https://ncbi.nlm.nih.gov/pubmed/26424893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1956-15.2015
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