MAPK signaling downstream to TLR4 contributes to paclitaxel-induced peripheral neuropathy

Toll-like receptor 4 (TLR4) has been implicated as a locus for initiation of paclitaxel related chemotherapy induced peripheral neuropathy (CIPN). This project explores the involvement of the immediate down-stream signal molecules in inducing paclitaxel CIPN. Mitogen-activated protein kinases (MAPK)...

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Bibliographische Detailangaben
Veröffentlicht in:Brain Behav Immun
Hauptverfasser: Li, Yan, Zhang, Hongmei, Kosturakis, Alyssa K., Cassidy, Ryan M., Zhang, Haijun, Kennamer-Chapman, Ross M., Jawad, Abdul Basit, Colomand, Cecilia M., Harrison, Daniel S., Dougherty, Patrick M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567501/
https://ncbi.nlm.nih.gov/pubmed/26065826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2015.06.003
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