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Evidence that spinal astrocytes but not microglia contribute to the pathogenesis of paclitaxel-induced painful neuropathy

Paclitaxel often induces persistent painful neuropathy as its most common treatment limiting side effect. Little is known concerning the underlying mechanisms. Given the prominent role of glial cells in many types of neuropathic pain, we investigated here the morphological and functional changes of...

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Detalles Bibliográficos
Main Authors: Zhang, Haijun, Yoon, Seo-Yeon, Zhang, Hongmei, Dougherty, Patrick M.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294066/
https://ncbi.nlm.nih.gov/pubmed/22285612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2011.12.002
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