Dorsal root ganglion neurons become hyperexcitable and increase expression of voltage-gated T-type calcium channels (Cav3.2) in paclitaxel-induced peripheral neuropathy

Here it is shown that paclitaxel induced neuropathy is associated with the development of spontaneous activity (SA) and hyperexcitability in DRG neurons that is paralleled by increased expression of low-voltage-activated calcium channels (T-type; Ca(v)3.2). The percentage of DRG neurons showing SA a...

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Detaylı Bibliyografya
Yayımlandı:Pain
Asıl Yazarlar: Li, Yan, Tatsui, Claudio Esteves, Rhines, Laurence D., North, Robert Y., Harrison, Daniel S., Cassidy, Ryan M., Johansson, Caj A., Kosturakis, Alyssa K., Edwards, Denaya D., Zhang, Hongmei, Dougherty, Patrick M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303135/
https://ncbi.nlm.nih.gov/pubmed/27902567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000774
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