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Dorsal root ganglion infiltration by macrophages contributes to paclitaxel chemotherapy induced peripheral neuropathy

Chemotherapy-induced peripheral neuropathy (CIPN) is a disruptive and persistent side-effect of cancer treatment with paclitaxel. Recent reports showed that paclitaxel treatment results in the activation of Toll-like receptor 4 (TLR4) signaling and increased expression of monocyte chemotactic protei...

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Vydáno v:J Pain
Hlavní autoři: Zhang, Hongmei, Li, Yan, de Carvalho-Barbosa, Marianna, Kavelaars, Annemieke, Heijnen, Cobi J., Albrecht, Phillip J., Dougherty, Patrick M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939513/
https://ncbi.nlm.nih.gov/pubmed/26979998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2016.02.011
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