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Enhanced Excitability of Primary Sensory Neurons and Altered Gene Expression of Neuronal Ion Channels in Dorsal Root Ganglion in Paclitaxel-Induced Peripheral Neuropathy

BACKGROUND: The mechanism of chemotherapy-induced peripheral neuropathy after paclitaxel treatment is not well understood. Given the poor penetration of paclitaxel into central nervous system, peripheral nervous system is most at risk. METHODS: Intrinsic membrane properties of dorsal root ganglion (...

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Detalhes bibliográficos
Main Authors: Zhang, Haijun, Dougherty, Patrick M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031279/
https://ncbi.nlm.nih.gov/pubmed/24534904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000176
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