DRG Voltage-Gated Sodium Channel 1.7 Is Upregulated in Paclitaxel-Induced Neuropathy in Rats and in Humans with Neuropathic Pain

Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse effect experienced by cancer patients receiving treatment with paclitaxel. The voltage-gated sodium channel 1.7 (Na(v)1.7) plays an important role in multiple preclinical models of neuropathic pain and in inherited human pain phen...

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Publicat a:J Neurosci
Autors principals: Li, Yan, North, Robert Y., Rhines, Laurence D., Tatsui, Claudio Esteves, Rao, Ganesh, Edwards, Denaya D., Cassidy, Ryan M., Harrison, Daniel S., Johansson, Caj A., Zhang, Hongmei, Dougherty, Patrick M.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792474/
https://ncbi.nlm.nih.gov/pubmed/29255002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0899-17.2017
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