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Reconciling depressed Ca(2+) sparks occurrence with enhanced RyR2 activity in failing mice cardiomyocytes
Abnormalities in cardiomyocyte Ca(2+) handling contribute to impaired contractile function in heart failure (HF). Experiments on single ryanodine receptors (RyRs) incorporated into lipid bilayers have indicated that RyRs from failing hearts are more active than those from healthy hearts. Here, we an...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | J Gen Physiol |
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Κύριοι συγγραφείς: | , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
The Rockefeller University Press
2015
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4586588/ https://ncbi.nlm.nih.gov/pubmed/26371209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511366 |
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