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Isoproterenol Increases the Fraction of Spark-Dependent RyR-Mediated Leak in Ventricular Myocytes

Recent research suggests that the diastolic ryanodine-receptor-mediated release of Ca(2+) (J(leak)) from the sarcoplasmic reticulum of ventricular myocytes occurs in spark and nonspark forms. Further information about the role(s) of these release manifestations is scarce, however. This study address...

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Detalhes bibliográficos
Main Authors: Santiago, Demetrio J., Ríos, Eduardo, Shannon, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591256/
https://ncbi.nlm.nih.gov/pubmed/23473480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.01.026
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