Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation

Pore-forming proteins are weapons often used by bacterial pathogens to breach the membrane barrier of target cells. Despite their critical role in infection important structural aspects of the mechanism of how these proteins assemble into pores remain unknown. Streptococcus pneumoniae is the world’s...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Lawrence, Sara L., Feil, Susanne C., Morton, Craig J., Farrand, Allison J., Mulhern, Terrence D., Gorman, Michael A., Wade, Kristin R., Tweten, Rodney K., Parker, Michael W.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585913/
https://ncbi.nlm.nih.gov/pubmed/26403197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14352
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