Structural Studies of Streptococcus pyogenes Streptolysin O Provide Insights into the Early Steps of Membrane Penetration

Cholesterol-dependent cytolysins (CDCs) are a large family of bacterial toxins that exhibit a dependence on the presence of membrane cholesterol in forming large pores in cell membranes. Significant changes in the three-dimensional structure of these toxins are necessary to convert the soluble monom...

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Vydáno v:J Mol Biol
Hlavní autoři: Feil, Susanne C., Ascher, David B., Kuiper, Michael J., Tweten, Rodney K., Parker, Michael W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323271/
https://ncbi.nlm.nih.gov/pubmed/24316049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.11.020
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