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eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes

BACKGROUND: Genome-wide association studies (GWASs) have identified various genes associated with asthma, yet, causal genes or single nucleotide polymorphisms (SNPs) remain elusive. We sought to dissect functional genes/SNPs for asthma by combining expression quantitative trait loci (eQTLs) and GWAS...

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Bibliografski detalji
Izdano u:Allergy
Glavni autori: Li, Xingnan, Hastie, Annette T., Hawkins, Gregory A., Moore, Wendy C., Ampleford, Elizabeth J., Milosevic, Jadranka, Li, Huashi, Busse, William W., Erzurum, Serpil C., Kaminski, Naftali, Wenzel, Sally E., Meyers, Deborah A., Bleecker, Eugene R.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583797/
https://ncbi.nlm.nih.gov/pubmed/26119467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.12683
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