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A Powerful Framework for Integrating eQTL and GWAS Summary Data

Two new gene-based association analysis methods, called PrediXcan and TWAS for GWAS individual-level and summary data, respectively, were recently proposed to integrate GWAS with eQTL data, alleviating two common problems in GWAS by boosting statistical power and facilitating biological interpretati...

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Bibliografische gegevens
Gepubliceerd in:Genetics
Hoofdauteurs: Xu, Zhiyuan, Wu, Chong, Wei, Peng, Pan, Wei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676241/
https://ncbi.nlm.nih.gov/pubmed/28893853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300270
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