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A Powerful Framework for Integrating eQTL and GWAS Summary Data
Two new gene-based association analysis methods, called PrediXcan and TWAS for GWAS individual-level and summary data, respectively, were recently proposed to integrate GWAS with eQTL data, alleviating two common problems in GWAS by boosting statistical power and facilitating biological interpretati...
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| Vydáno v: | Genetics |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Genetics Society of America
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5676241/ https://ncbi.nlm.nih.gov/pubmed/28893853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300270 |
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