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Integration of methylation QTL and enhancer–target gene maps with schizophrenia GWAS summary results identifies novel genes

MOTIVATION: Most trait-associated genetic variants identified in genome-wide association studies (GWASs) are located in non-coding regions of the genome and thought to act through their regulatory roles. RESULTS: To account for enriched association signals in DNA regulatory elements, we propose a no...

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Foilsithe in:Bioinformatics
Main Authors: Wu, Chong, Pan, Wei
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761938/
https://ncbi.nlm.nih.gov/pubmed/30850848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz161
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