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Integration of Enhancer-Promoter Interactions with GWAS Summary Results Identifies Novel Schizophrenia-Associated Genes and Pathways

It remains challenging to boost statistical power of genome-wide association studies (GWASs) to identify more risk variants or loci that can account for “missing heritability.” Furthermore, since most identified variants are not in gene-coding regions, a biological interpretation of their function i...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Wu, Chong, Pan, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028261/
https://ncbi.nlm.nih.gov/pubmed/29728367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.300805
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