eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes

BACKGROUND: Genome-wide association studies (GWASs) have identified various genes associated with asthma, yet, causal genes or single nucleotide polymorphisms (SNPs) remain elusive. We sought to dissect functional genes/SNPs for asthma by combining expression quantitative trait loci (eQTLs) and GWAS...

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Detalhes bibliográficos
Publicado no:Allergy
Main Authors: Li, Xingnan, Hastie, Annette T., Hawkins, Gregory A., Moore, Wendy C., Ampleford, Elizabeth J., Milosevic, Jadranka, Li, Huashi, Busse, William W., Erzurum, Serpil C., Kaminski, Naftali, Wenzel, Sally E., Meyers, Deborah A., Bleecker, Eugene R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583797/
https://ncbi.nlm.nih.gov/pubmed/26119467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.12683
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