Transcriptional Regulation of the Astrocytic Excitatory Amino Acid Transporter 1 (EAAT1) via NF-κB and Yin Yang 1 (YY1)

Astrocytic glutamate transporter excitatory amino acid transporter (EAAT) 1, also known as glutamate aspartate transporter (GLAST) in rodents, is one of two glial glutamate transporters that are responsible for removing excess glutamate from synaptic clefts to prevent excitotoxic neuronal death. Des...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Karki, Pratap, Kim, Clifford, Smith, Keisha, Son, Deok-Soo, Aschner, Michael, Lee, Eunsook
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Molecular Bases of Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583050/
https://ncbi.nlm.nih.gov/pubmed/26269591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.649327
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