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Genetic dys-regulation of astrocytic glutamate transporter EAAT2 and its implications in neurological disorders and manganese toxicity

Astrocytic glutamate transporters, the excitatory amino acid transporter (EAAT) 2 and EAAT1 [glutamate transporter 1 (GLT-1) and glutamate aspartate transporter (GLAST) in rodents, respectively], are the main transporters for maintaining optimal glutamate levels in the synaptic clefts by taking up m...

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Detalhes bibliográficos
Publicado no:Neurochem Res
Main Authors: Karki, Pratap, Smith, Keisha, Johnson, James, Aschner, Michael, Lee, Eunsook
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308576/
https://ncbi.nlm.nih.gov/pubmed/25064045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-014-1391-2
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