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Role of transcription factor yin yang 1 in manganese-induced reduction of astrocytic glutamate transporters: putative mechanism for manganese-induced neurotoxicity

Astrocytes are the most abundant non-neuronal glial cells in the brain. Once relegated to a mere supportive role for neurons, contemporary dogmas ascribe multiple active roles for these cells in central nervous system (CNS) function, including maintenance of optimal glutamate levels in synapses. Reg...

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Bibliographic Details
Published in:Neurochem Int
Main Authors: Karki, Pratap, Smith, Keisha, Johnson, James, Aschner, Michael, Lee, Eunsook
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326602/
https://ncbi.nlm.nih.gov/pubmed/25128239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2014.08.002
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