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Arundic acid increases expression and function of astrocytic glutamate transporter EAAT1 via the ERK, Akt and NF-κB pathways
Glutamate is the major excitatory neurotransmitter in the brain, but excessive synaptic glutamate must be removed to prevent excitotoxic injury and death. Two astrocytic glutamate transporters, excitatory amino acid transporter (EAAT) 1 and 2, play a major role in eliminating excess glutamate from t...
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| Publicado no: | Mol Neurobiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5964991/ https://ncbi.nlm.nih.gov/pubmed/28812276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-017-0709-x |
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