Paclitaxel tumor priming promotes delivery and transfection of intravenous lipid-siRNA in pancreatic tumors

The major barrier for using small interfering RNA (siRNA) as cancer therapeutics is the inadequate delivery and transfection in solid tumors. We have previously shown that paclitaxel tumor priming, by inducing apoptosis, expands the tumor interstitial space, improves the penetration and dispersion o...

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Bibliografiska uppgifter
I publikationen:J Control Release
Huvudupphovsmän: Wang, Jie, Lu, Ze, Wang, Junfeng, Cui, Minjian, Yeung, Bertrand Z., Cole, David J., Wientjes, M. Guillaume, Au, Jessie L.-S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582943/
https://ncbi.nlm.nih.gov/pubmed/26272765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.08.012
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