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Delivery of siRNA Therapeutics: Barriers and Carriers

RNA interference is a naturally occurring endogenous regulatory process where short double-stranded RNA causes sequence-specific posttranscriptional gene silencing. Small interference RNA (siRNA) represents a promising therapeutic strategy. Clinical evaluations of siRNA therapeutics in locoregional...

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Detalhes bibliográficos
Main Authors: Wang, Jie, Lu, Ze, Wientjes, M. Guillaume, Au, Jessie L.-S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977003/
https://ncbi.nlm.nih.gov/pubmed/20544328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9210-4
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