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Paclitaxel tumor priming promotes delivery and transfection of intravenous lipid-siRNA in pancreatic tumors
The major barrier for using small interfering RNA (siRNA) as cancer therapeutics is the inadequate delivery and transfection in solid tumors. We have previously shown that paclitaxel tumor priming, by inducing apoptosis, expands the tumor interstitial space, improves the penetration and dispersion o...
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| 出版年: | J Control Release |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4582943/ https://ncbi.nlm.nih.gov/pubmed/26272765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.08.012 |
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