Paclitaxel tumor priming promotes delivery and transfection of intravenous lipid-siRNA in pancreatic tumors

The major barrier for using small interfering RNA (siRNA) as cancer therapeutics is the inadequate delivery and transfection in solid tumors. We have previously shown that paclitaxel tumor priming, by inducing apoptosis, expands the tumor interstitial space, improves the penetration and dispersion o...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Wang, Jie, Lu, Ze, Wang, Junfeng, Cui, Minjian, Yeung, Bertrand Z., Cole, David J., Wientjes, M. Guillaume, Au, Jessie L.-S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582943/
https://ncbi.nlm.nih.gov/pubmed/26272765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.08.012
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