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Tumor priming enhances siRNA delivery and transfection in intraperitoneal tumors

Cancers originating from digestive system account for 290,000 or ~20% of all new cancer cases annually in the US. We previously developed paclitaxel-loaded tumor-penetrating microparticles (TPM) for intraperitoneal (IP) treatment of peritoneal tumors [1–3]. TPM is undergoing NIH-supported IND-enabli...

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Main Authors: Wang, Jie, Lu, Ze, Yeung, Bertrand Z., Wientjes, M. Guillaume, Cole, David J., Au, Jessie L.-S.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994124/
https://ncbi.nlm.nih.gov/pubmed/24462901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.01.012
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