Wird geladen...

Dynamic Contacts of U2, RES, Cwc25, Prp8 and Prp45 Proteins with the Pre-mRNA Branch-Site and 3' Splice Site during Catalytic Activation and Step 1 Catalysis in Yeast Spliceosomes

Little is known about contacts in the spliceosome between proteins and intron nucleotides surrounding the pre-mRNA branch-site and their dynamics during splicing. We investigated protein-pre-mRNA interactions by UV-induced crosslinking of purified yeast B(act) spliceosomes formed on site-specificall...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Schneider, Cornelius, Agafonov, Dmitry E., Schmitzová, Jana, Hartmuth, Klaus, Fabrizio, Patrizia, Lührmann, Reinhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579134/
https://ncbi.nlm.nih.gov/pubmed/26393790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005539
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!