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Effects of Repeated Morphine on Intracranial Self-Stimulation in Male Rats In the Absence or Presence of a Noxious Pain Stimulus

Research on opioid analgesics such as morphine suggests that expression of abuse-related effects increases with repeated exposure. Repeated exposure to opioids often occurs clinically in the context of pain management, and a major concern for clinicians is the risk of iatrogenic addiction and depend...

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Библиографические подробности
Опубликовано в: :Exp Clin Psychopharmacol
Главные авторы: Miller, Laurence L., Altarifi, Ahmad A., Negus, S. Stevens
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578993/
https://ncbi.nlm.nih.gov/pubmed/26375515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/pha0000042
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